CREST members develop real-world evidence about the health effects of medications and other medical products, and prepare the next generation of pharmacoepidemiology leaders. CREST is an academic partner to the Food and Drug Administration (FDA)-funded Sentinel Initiative. CREST members are also editors of the journal Pharmacoepidemiology and Drug Safety, and the books Pharmacoepidemiology, 6th edition and Textbook of Pharmacoepidemiology, 3rd edition.